North American Veterinary Licensing Examination (NAVLE) Practice Test

The significant clinical sign associated with canine parvovirus infection is severe gastrointestinal symptoms, primarily manifested as vomiting and diarrhea, often resulting in bloody feces. Although pyoderma refers to a bacterial skin infection that can occur in dogs, it is not directly indicative of canine parvovirus.

Canine parvovirus attacks rapidly dividing cells, particularly in the gastrointestinal tract, leading to damage to the intestinal lining and severe enteritis. This results in clinical presentation involving significant gastrointestinal distress rather than skin issues or respiratory or neurological signs. Severe sweating is not characteristic of parvovirus; dogs primarily show signs of distress through vomiting and diarrhea. Acute respiratory distress and neurological signs also do not correlate with parvovirus infection. Therefore, acknowledging the prominent gastrointestinal clinical signs will help in identifying and diagnosing this viral infection accurately.